Filamen

Filamen. Filamin A is a large cytoplasmic protein that crosslinks actin filaments into orthogonal arrays and fastens the vWF receptor (GPIbIXV) to the underlying filamentous actin Filamin subunits are elongated strands composed primarily of 24 repeats each ~ 100 amino acids in length that are folded into IgGlike beta barrels.

Filamin is an actinbinding protein that was first recognized (and named) for its filamentous colocalization with actin stress fibersFilamin molecules are naturally found in cells as elongated Vshaped dimers (ie two linked filamin molecules) that contain several immunoglobulinlike domains for protein interactions aminoterminal actinbinding domains (ABD) composed of.

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Filamin an overview ScienceDirect Topics

Filament definition a very fine thread or threadlike structure a fiber or fibril filaments of gold See more.

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